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Cortical Electrophysiology of Response Inhibition in Parkinson's Disease

Studying brain response control in Parkinson's Disease.

Recruiting
45-75 years
All
Phase 4

This study is for people with Parkinson's Disease (PD) and healthy controls. It looks at how a treatment called deep brain stimulation (DBS) affects the brain's ability to control actions. In people with PD, it can be hard to stop certain movements or actions, like stopping from moving when a car is coming. DBS is a surgery where a device is placed in the brain to help control movement. This study examines if DBS affects thinking and behavior.

Key Points:

  • PD patients will be in the study for up to 18 months; healthy controls visit twice.
  • Study checks how DBS affects stopping movements, especially impulsive actions.
  • Participants won't change their usual PD treatments for this study.

Eligible PD patients will have diagnosed PD and meet certain health criteria. The study requires some PD patients to test DBS settings and medication states. Healthy participants should be aged 45-75 without mental health issues. The study aims to improve understanding of how brain areas work in controlling actions with PD and DBS.

Study details
    Parkinson Disease

NCT06234995

Emory University

12 September 2026

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