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Optical Neuroimaging and Cognition

Join a study on brain imaging and thinking skills.

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This study looks at dementia, a condition affecting memory, thinking, and behavior. Researchers want to find new ways to study brain changes without using big machines that are loud and expensive. They are using a tool called Near-Infrared Spectroscopy (NIRS). This tool uses light to look at oxygen levels and metabolism in the brain. NIRS is quiet, safe, and can be used at home. The study will involve people with types of dementia like Alzheimer's, Lewy Body Dementia, and also those with Mild Cognitive Impairment (MCI), which is an early stage of memory loss. Healthy people will also be studied for comparison. Participants will take cognitive tests while their brain activity is measured. This research might help discover new ways to diagnose dementia earlier and more accurately.

  • Study involves 200 participants: 25 with Alzheimer's, 25 with Lewy Body Dementia, 50 with MCI, and 100 healthy individuals.
  • Cognitive tests and brain monitoring using NIRS will be done.
  • Participants must have good English and someone to help during tests, if in a patient group.
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Study details
    Dementia With Lewy Bodies
    Alzheimer Disease
    Mild Cognitive Impairment

NCT05460143

University of Cambridge

17 April 2026

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