This study explores a unique approach to treating Parkinson's Disease (PD) and Multiple System Atrophy (MSA). It involves using a small piece of your own nerve, called the sural nerve, from your leg and placing it into a part of the brain called the substantia nigra. The study aims to see if this can help repair damaged brain cells. Seven participants will join. Four will receive the nerve graft, and three will have a sham surgery (a pretend surgery to compare results). The trial is double-blind, meaning neither the participants nor the researchers know who receives the actual treatment at first. This study helps plan future trials and lasts for one year.
- Participants must be in the early stages of PD or MSA and aged 40-75.
- Involves surgery and follow-up visits for one year.
- Participants might receive a placebo surgery.