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Effect and Mechanism of Brain Stimulation for Parkinson's Disease With Cognitive Impairment

Studying brain stimulation effects on Parkinson's with cognitive issues.

Recruiting
75 years and younger
All
Phase N/A

This study explores how two brain stimulation methods, DBS (Deep Brain Stimulation) and TMS (Transcranial Magnetic Stimulation), can help people with Parkinson's Disease (PD) who also have trouble with thinking and memory. The study uses special pictures of the brain to see how it changes after these treatments. This could help doctors choose the best spots in the brain to treat and improve patients' symptoms.

**Deep Brain Stimulation (DBS)** involves surgery to place electrodes in the brain, while **Transcranial Magnetic Stimulation (TMS)** uses magnetic fields to stimulate brain cells. The study aims to understand how these methods change brain networks and improve thinking problems in PD patients.

Key Points:

  • The study requires participants to have had Parkinson's for over 5 years.
  • Participants must not have severe thinking or mental health issues.
  • The study might help find better treatment areas for brain stimulation.
Study details
    Parkinson Disease
    Cognitive Impairment

NCT06090682

Tianjin Huanhu Hospital

17 April 2026

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