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Impact of Frequency-specific Subthalamic Nucleus Subregion Stimulation on Inhibitory Control in Parkinson's Disease

Studying brain stimulation effects on Parkinson's disease symptoms.

Recruiting
40-80 years
All
Phase N/A

This study focuses on Parkinson's Disease (PD), a condition with both movement and mental symptoms. A common mental issue is cognitive impairment, where thinking processes are affected, often leading to dementia. One key problem is inhibitory control, making it hard for people to stop impulsive actions and stay focused. The Subthalamic Nucleus (STN) in the brain is important in PD. It has different parts that control movement and thinking. Deep Brain Stimulation (DBS) is a known treatment using electrical pulses to help with movement symptoms. This study will test different electrical frequencies on various STN parts to see if it helps with thinking issues.

  • Participants will be 40-80 years old and must have PD and be eligible for DBS surgery.
  • People with severe mental conditions or other major health issues can't join.
  • The study will involve tests to see how well participants can control their actions under different brain stimulation settings.
Study details
    Parkinson Disease
    Deep Brain Stimulation

NCT07022522

Beijing Tiantan Hospital

17 April 2026

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