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Choice of Anesthesia in Microelectrode Recording Guided Deep Brain Stimulation for Parkinson's Disease

Exploring anesthesia options in Parkinson's deep brain stimulation study.

Recruiting
50-80 years
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)
Study Summary: This study looks at two types of anesthesia for Parkinson's Disease (PD) surgery called Deep Brain Stimulation (DBS) in the subthalamic nucleus (STN). The study compares general anesthesia (using a medicine called desflurane) and conscious sedation (using a medicine called dexmedetomidine). The main goal is to see how these medicines affect electrical signals in the brain during surgery. These signals are important for the surgery's success. Key Points:
  • This study involves two groups: one will receive conscious sedation and the other will receive general anesthesia.
  • The study observes patients' brain activity during surgery and compares the results from both anesthesia types.
  • Participants will be followed for 6 months after surgery to assess outcomes.
Eligibility: Participants must be 50-80 years old, have Parkinson's disease, and be approved for bilateral STN-DBS surgery. They should not have conditions like sleep apnea, severe anxiety, or allergies to anesthetics. They should also not have severe organ dysfunction or a high body mass index (BMI).
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Study details
    PD - Parkinson's Disease
    Dexmedetomidine
    Desflurane
    Deep Brain Stimulation

NCT05550714

Beijing Tiantan Hospital

17 April 2026

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