This study is testing a new treatment called **Exablate MRgFUS subthalamotomy** for people with early-stage Parkinson's Disease (ESPD). This treatment uses focused ultrasound guided by MRI to target specific brain areas. Participants will either receive this treatment or the best available medical care. Participants must be between 30 and 65 years old and have had Parkinson's for at least a year but less than five years. Participants need to be able to attend all study visits and communicate during the treatment. **Key Points:** - **Study Duration:** Participants will be involved in a series of visits; the exact number isn't specified. - **Safety and Effectiveness:** The study aims to test if the treatment is safe and works well compared to regular care. - **Eligibility:** Participants must meet specific health criteria and not have certain conditions, like severe depression or other brain diseases. This study helps researchers understand if this new treatment can be a good alternative for people with early Parkinson's.