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Comparison of Different Non-invasive Electrical Stimulation Protocols to Facilitate Rehabilitation in Parkinson's Disease Subjects With Postural Instability and Gait Disorders

Exploring electrical stimulation to help Parkinson's patients with balance and walking issues.

Recruiting
45-85 years
All
Phase N/A

This study is looking at Parkinson's disease (PD) patients who have trouble with balance and walking. The study involves two groups of PD patients and a group of healthy people. PD patients will be split into two groups: REHAB+SHAM and REHAB+STIM. Both groups will do special exercises to help with walking and balance. The difference is that the REHAB+STIM group will also receive real electrical stimulation called transcranial Direct Current Stimulation (tDCS) and trans-spinal Direct Current Stimulation (tsDCS), while the REHAB+SHAM group will get a fake stimulation called SHAM, which feels like the real thing but does not actually stimulate the brain.

**Key Points**:

  • Participants will be involved for 28 weeks, including breaks and follow-up visits.
  • Sessions are held 3 times a week, each lasting about 1 hour.
  • Participants will undergo tests like brain scans and blood tests to check improvements and safety.
Study details
    Parkinson Disease

NCT06868160

IRCCS San Raffaele

17 April 2026

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