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Personalized Repetitive Transcranial Magnetic Stimulation (rTMS) in Cognitive Fluctuations of Dementia With Lewy Bodies (DLB): Proof of Concept

Exploring rTMS for dementia-related cognitive changes in Lewy Bodies.

Recruiting
45 years and older
All
Phase N/A
Personalized rTMS in Cognitive Fluctuations of DLB Study: This study involves forty patients with Dementia with Lewy Bodies (DLB), a condition affecting memory and thinking. We use a technique called repetitive transcranial magnetic stimulation (rTMS), which uses magnets to stimulate the brain without surgery. The goal is to see if it helps with changes in alertness and awareness that people with DLB often experience. Participants will have 37 visits, including two sessions of rTMS per visit, for a total of 20 rTMS sessions per patient. They'll also have brain scans (MRI) and tests to check for changes in symptoms before and after the rTMS. Key Points:
  • This study involves 37 visits in total, including multiple brain scans and assessments.
  • Participants will undergo a total of 20 rTMS sessions.
  • Patients need to have a caregiver available to assist with the study requirements.
It's important to understand the study's aims and risks, and participants should be able to give informed consent. Some people cannot join, such as those with a history of seizures or certain medical devices.
Study details
    Dementia With Lewy Bodies Diagnosis
    Significant Cognitive Fluctuations in DLB

NCT05138588

University Hospital, Strasbourg, France

29 August 2026

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