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Constant Current Versus Constant Voltage Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson's Disease

Comparing two brain stimulation methods for Parkinson's: constant current vs. voltage.

Recruiting
18-75 years
All
Phase N/A

This study is for people with Parkinson's disease (PD), a brain disorder that affects movement. It checks two ways of using a device called Deep Brain Stimulation (DBS): current mode and voltage mode. DBS is a treatment that sends electrical signals to a part of the brain called the subthalamic nucleus to help control PD symptoms. The study wants to see which way works better and is easier for doctors and patients to use.

About 180 people will join this study from different locations, and it will last for 12 months. People aged 18 to 75 who have had DBS surgery but haven't turned it on yet can participate. But, it’s not for those with mental health issues, pregnant women, or other serious health conditions.

  • Duration: Study lasts for 12 months with follow-up visits.
  • Participants: 180 people from up to 14 sites.
  • Eligibility: Ages 18-75 with PD, after DBS surgery, but not powered on yet.
Study details
    Parkinson's Disease (PD)

NCT06742450

Xuanwu Hospital, Beijing

17 April 2026

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