Image

Efficacy and Safety of Entacapone Combined With Madopar in the Treatment of Early Parkinson's Disease: An Observational, Multicenter, Case-Control Study

Study on Entacapone and Madopar for early Parkinson's Disease.

Recruiting
18-80 years
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study looks at how safe and effective it is to add a drug called Entacapone to another medicine called Madopar (which is levodopa/benserazide) for treating early Parkinson's disease (PD). Parkinson's disease is a condition that affects movement, making it slow or stiff. The study will involve patients aged 18 to 80 in China who are at the early stages of PD. Participants will be monitored for 24 weeks to see how their movement improves and if there are any side effects.

Participants will be divided into two groups: one will take Madopar with Entacapone, and the other will only take Madopar. The main focus will be on changes in movement, but the study will also check daily activities, quality of life, and any unwanted effects. No changes to treatment will be forced by the study; doctors will decide as usual. The study expects to start in June 2025 and end by April 2027.

  • The study lasts 24 weeks.
  • No new treatments will be forced; doctors decide the care plan.
  • Participants must be between 18-80 years old and meet specific health criteria.
Print
Study details
    Parkinson Disease (PD)

NCT06928519

Yousheng Xiao

17 April 2026

Contact a study center
Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.