Orthostatic hypotension (OH) and orthostatic intolerance (OI) are conditions that make people feel dizzy or faint when standing up because their blood pressure drops. Many older adults (30% of those over 65) have these issues, which can lead to serious health problems like heart disease. Current treatments don't always work well and can have side effects. The STAND-UP Study tests a new way to help by opening narrow veins above the heart to improve blood flow, possibly easing symptoms.
The study lasts for 2 years and is for adults 18+ with OH or OI not helped by other treatments. Participants will have imaging tests to check their veins. If needed, a procedure using a thin tube (catheter) and tiny balloon (angioplasty) or mesh tube (stent) will widen the veins. This takes a few hours and is done under local anesthesia. There are follow-ups at various times over two years to check on progress and safety.
- Participants must be 18+ and not pregnant or breastfeeding.
- Risks include bleeding and infection, but these are rare.
- No cost for the procedure; insurance or the clinic covers it.
Contact Dr. Karthikeyan Arcot at St. Francis Hospital for more details.