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Sequential Treatment With GEMBRAX and Then FOLFIRINOX Followed by Stereotactic MRI-guided Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

Investigating Chemotherapy and Radiotherapy for Locally Advanced Pancreatic Cancer

Recruiting
18-75 years
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates the use of sequential chemotherapy and radiotherapy in patients with locally advanced pancreatic cancer. The purpose of this study is to evaluate the effectiveness of a specific sequence of treatments involving two chemotherapy regimens followed by targeted radiotherapy.

The study focuses on assessing the safety and effectiveness of combining chemotherapy with advanced radiotherapy techniques. It evaluates how well these treatments work together to manage the condition and improve patient outcomes.

  • Who can participate: Adults aged 18 to 75 with confirmed pancreatic adenocarcinoma, non-resectable tumors, and ECOG performance status of 0 or 1 may participate. Patients must not have metastatic cancer and need to meet specific health criteria.
  • Study details: Participants will receive chemotherapy followed by radiotherapy. A placebo is not used in this study. The study involves using MRI-guided radiotherapy to target cancer while protecting healthy organs.
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Study details
    Locally Advanced Pancreatic Adenocarcinoma

NCT04570943

Institut du Cancer de Montpellier - Val d'Aurelle

31 July 2026

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