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Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

Investigational Medication Study for Safety and Tolerability in Pancreatic Adenocarcinoma and Non-Small Cell Lung Cancer

Recruiting
18 years and older
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates pancreatic adenocarcinoma and non-small cell lung cancer. The purpose of this study is to evaluate the investigational medication in combination with other treatments.

The study evaluates the safety, tolerability, and effectiveness of the investigational medication. It focuses on understanding how the medication works in the body and its potential effects.

  • Who can participate: Adults aged 18 and older with pancreatic adenocarcinoma or non-small cell lung cancer can participate. Eligibility requires an ECOG performance status of 0 or 1 and adequate organ function.
  • Study details: Participants will take the investigational medication in combination with other treatments.
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Study details
    PDAC
    PDAC - Pancreatic Ductal Adenocarcinoma
    NSCLC
    RAS Mutation
    MTAP Deletion
    Lung Cancer
    Pancreatic Cancer Metastatic
    Thoracic Cancer

NCT06922591

Tango Therapeutics, Inc.

31 July 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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