This study investigates the use of psilocybin-assisted psychotherapy for individuals with adjustment disorder due to a cancer diagnosis.

The purpose of this study is to evaluate the safety and effectiveness of psilocybin-assisted psychotherapy. Researchers will assess how well the treatment works for managing symptoms of adjustment disorder in cancer patients.

• Who can participate: Adults aged 18 to 80 years with adjustment disorder due to cancer diagnosis can participate. Key eligibility includes a diagnosis of adjustment disorder, moderate anxiety, and a minimum life expectancy of 6 months.
• Study details: Participants will have sessions of psilocybin-assisted psychotherapy. The study involves different doses of an investigational medication. Some participants may receive a placebo, an inactive substance that looks like the investigational medicine but does not contain any medicine.
• Study timelines and visits: The study will last 3 months. The study requires 5 visits.