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Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Study of Investigational Medication for Stomach and Intestinal Tumors

Recruiting
18 years and older
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates gastrointestinal solid tumors. It evaluates the safety and tolerability of investigational medications in combination with standard treatments or new agents.

The study focuses on assessing the safety, tolerability, and potential antitumor effects of the investigational medications. It also examines how these medications are processed in the body.

  • Who can participate: Adults aged 18 and older with specific RAS-mutated gastrointestinal tumors may participate. Participants must have adequate organ function and no major surgery within 28 days before joining.
  • Study details: Participants will receive investigational medications combined with standard treatments or agents. Some participants may receive a placebo.
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Study details
    Colorectal Cancer
    CRC
    Pancreatic Ductal Adenocarcinoma
    PDAC
    Gastrointestinal Cancer
    Metastatic Pancreatic Ductal Adenocarcinoma

NCT06445062

Revolution Medicines, Inc.

8 August 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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