Image

iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation

Investigating iExosomes for Metastatic Pancreatic Cancer with KrasG12D Mutation

Recruiting
18 years and older
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates the use of iExosomes in treating metastatic pancreatic cancer with KrasG12D mutation. The purpose of this study is to determine the best dose and observe any side effects of these exosomes in patients.

The study evaluates the safety and effectiveness of iExosomes in patients. Researchers are interested in understanding how these exosomes behave in the body and their impact on the disease.

  • Who can participate: Adults with metastatic pancreatic cancer having the KrasG12D mutation can participate. Participants should have experienced disease progression or stable disease after prior treatments and meet specific health criteria.
  • Study details: Participants will receive the investigational medication intravenously on specific days over a 14-day cycle. Some may receive a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.
Print
Study details
    KRAS NP_004976.2:p.G12D
    Metastatic Pancreatic Adenocarcinoma
    Pancreatic Ductal Adenocarcinoma
    Stage IV Pancreatic Cancer AJCC v8

NCT03608631

M.D. Anderson Cancer Center

12 September 2026

Contact a study center
Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.