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A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

Study on Investigational Medication for Solid Tumors with p53 R175H Mutation

Recruiting
18 years and older
All
Phase 1

This study investigates solid tumors with the p53 R175H mutation. It focuses on understanding how the investigational medication works in patients with this condition.

The study evaluates the safety, tolerability, and activity of the investigational medication. This study investigates how the body processes the medication and its effects.

  • Who can participate: Adults aged 18 and older with advanced solid tumors that have a p53 R175H mutation can participate. Participants must be HLA-A*02:01 positive and have tumors that progressed after standard therapy.
  • Study details: Participants will receive an investigational medication to study its effects. The study will explore safety and how the body responds to the medication.
Study details
    Advanced Solid Tumor
    Unresectable Solid Tumor
    Metastatic Solid Tumor
    Colorectal Adenocarcinoma
    Pancreatic Adenocarcinoma
    Lung Cancer
    Ovarian Cancer
    Breast Cancer
    Head and Neck Squamous Cell Carcinoma
    Prostate Cancer
    Bladder Cancer

NCT06778863

Clasp Therapeutics, Inc.

31 July 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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