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Evaluating NALIRIFOX vs Modified Gemcitabine, Nab-Paclitaxel and Cisplatin in Patients With Locally Advanced and Metastatic Pancreatic Adenocarcinoma

Investigating Treatment Options for Locally Advanced and Metastatic Pancreatic Cancer

Recruiting
18 years and older
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates pancreatic ductal adenocarcinoma. It compares two treatment options to see which is more effective for patients who have not received previous treatment.

The study evaluates the overall response rate and safety of two different chemotherapy combinations. It looks at how well patients respond to these treatments and their effects on the condition.

  • Who can participate: Adults aged 18 and older with locally advanced or metastatic pancreatic ductal adenocarcinoma that has not been treated before can participate.
  • Study details: Participants will receive either the NALIRIFOX treatment or the mGAP treatment. The study will measure the effectiveness of these treatments. An inactive substance called a placebo is not used in this study.
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Study details
    Metastatic Pancreatic Adenocarcinoma
    Locally Advanced Pancreatic Adenocarcinoma

NCT07076212

Medical University of South Carolina

31 July 2026

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