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Exploratory Clinical Study of HRS-4642 Combined With Adebrelimab in the Treatment of Advanced Pancreatic Ductal Adenocarcinoma

Research Study of Investigational Medication Combination for Advanced Pancreatic Cancer

Recruiting
18-75 years
All
Phase 1/2

This study investigates advanced pancreatic ductal adenocarcinoma. It evaluates the combination of investigational medication HRS-4642 and adebelimab.

The study focuses on understanding the safety, tolerability, and effectiveness of the treatment combination.

  • Who can participate: Adults aged 18 to 75 with advanced pancreatic ductal adenocarcinoma may participate. Eligibility requires at least one measurable lesion and an ECOG Performance Status of 0 or 1.
  • Study details: Participants will receive a combination of investigational medications. Some may receive a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.
Study details
    Pancreatic Cancer

NCT06427239

Fudan University

30 July 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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