Image

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

Investigation of Investigational Medications in Advanced KRAS G12C Mutant Solid Tumors

Recruiting
18 years and older
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates KRAS G12C-mutated solid tumors. The purpose of this study is to evaluate the safety and tolerability of investigational medications Elironrasib and Daraxonrasib, used alone and together.

The study focuses on understanding how the investigational medications are processed in the body and their effects on the tumors. Researchers will assess the safety and effectiveness of the treatments.

  • Who can participate: Adults aged 18 and older with advanced or metastatic KRAS G12C-mutated solid tumors can participate. Participants should have an ECOG performance status of 0 or 1 and adequate organ function.
  • Study details: Participants will receive investigational medications as monotherapies or in combination.
Print
Study details
    Non-Small Cell Lung Cancer (NSCLC)
    Colorectal Cancer
    Pancreatic Ductal Adenocarcinoma

NCT06128551

Revolution Medicines, Inc.

8 August 2026

Contact a study center
Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.