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Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors

Evaluating Safety and Tolerability of Investigational Medication in Advanced Solid Tumors

Recruiting
18 years and older
All
Phase 1

This study investigates advanced solid tumors with known Ly6E expression, including non-small cell lung cancer, triple-negative breast cancer, epithelial ovarian carcinoma, squamous cell carcinoma of the head and neck, pancreatic ductal adenocarcinoma, and gastric cancer.

The study evaluates the safety, tolerability, pharmacokinetics, and preliminary clinical activity of an investigational medication in participants.

  • Who can participate: Adults 18 years and older with advanced solid tumors that have high Ly6E expression and are not treatable with standard therapies may qualify. Participants must have a good performance status and normal organ function.
  • Study details: Participants will receive an investigational medication.
Study details
    Advanced Solid Tumors

NCT07360314

EMD Serono Research & Development Institute, Inc.

12 September 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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