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The Vanguard Study: Testing a New Way to Screen for Cancer

Investigating Multi-Cancer Detection Tests for Cancer Identification

Recruiting
45-75 years
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates the use of multi-cancer detection (MCD) tests for screening multiple cancers simultaneously. The purpose of this study is to explore how these tests can be used to detect cancer in adults aged 45 to 75 who do not currently have cancer.

Researchers will evaluate the performance of MCD tests as screening tools. This includes understanding how patients and doctors make decisions based on test results and examining the effectiveness of these tests in identifying cancers early.

  • Who can participate: Adults aged 45 to 75 who can provide blood samples and allow medical record access may participate. Participants must complete consent and questionnaires in English, Spanish, or Arabic.
  • Study details: Participants will provide blood samples for MCD testing at enrollment and one year later. An inactive substance will not be used in this study.
  • Study timelines and visits: The study will last 1 year. The study requires 2 visits.
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Study details
    Bladder Carcinoma
    Breast Carcinoma
    Colorectal Carcinoma
    Esophageal Carcinoma
    Gastric Carcinoma
    Liver Carcinoma
    Lung Carcinoma
    Malignant Solid Neoplasm
    Ovarian Carcinoma
    Pancreatic Carcinoma
    Prostate Carcinoma

NCT06995898

National Cancer Institute (NCI)

12 September 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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