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18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

Investigational PET Imaging for Cancer Detection

Recruiting
18-120 years
All
Phase 2

This study investigates cancer detection using a new type of PET imaging called [18F]FAPI-74. The purpose of this study is to explore its effectiveness in identifying certain types of cancer.

The study focuses on evaluating the ability of [18F]FAPI-74 PET imaging to detect cancer compared to other standard imaging methods. Researchers are interested in seeing if this investigational imaging method can provide better visualization of tumors.

  • Who can participate: Adults aged 18 or older with specific types of cancer such as pancreatic, liver, or ovarian cancer may participate. Participants must be scheduled for cancer treatment and meet certain health criteria.
  • Study details: Participants will undergo PET imaging using [18F]FAPI-74, which involves a tracer injected into the body before scanning.
  • Study timelines: The study will last 2 years.
Study details
    Sarcoma
    Small Cell Lung Cancer or Extrapulmonary Neuroendocrine Cancer (EP-NEC)
    Mesothelioma
    Pheochromocytoma/Paraganglioma (PPGL)
    Pancreatic Ductal Adenocarcinoma
    Ovarian Cancer
    Hepatocellular Carcinoma
    Gastric Cancer
    Cholangiocarcinoma
    Bladder Cancer

NCT06503146

National Cancer Institute (NCI)

31 July 2026

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