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Bile Omics for Diagnosing Indeterminate Biliary Strictures

Investigating Biliary Strictures Using Bile-Based Molecular Analysis

Recruiting
18-90 years
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates indeterminate biliary strictures. It explores the potential of using bile samples to find molecular markers linked to biliary malignancies.

The focus is to evaluate if combining bile-based omics with traditional biliary brush cytology and biopsy can improve diagnostic accuracy. This study evaluates the effectiveness of this combined approach.

  • Who can participate: Adults aged 18 to 90 with indeterminate biliary strictures who have undergone ERCP with biliary biopsy or brush cytology can participate. Exclusion criteria include coagulation disorders, pregnancy, or unrelated malignancies.
  • Study details: Participants will provide bile samples for molecular marker screening.
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Study details
    Cholangiocarcinoma
    Gallbladder Cancer and Extrahepatic Cholangiocarcinoma
    Pancreatic Cancer
    Bile Duct Strictures of Unknown Origin
    Bile Duct Strictures

NCT07007832

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

31 July 2026

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