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Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

Investigation of Tumor Cell and DNA Detection in Blood, Urine, and Bone Marrow for Cancer Patients

Recruiting
18 years and older
All
Phase N/A

This study investigates the detection of circulating and disseminated tumor cells (CTCs/DTCs) and circulating cell-free (cf) DNA in the blood, urine, and bone marrow of patients with solid primary cancers. The purpose is to increase understanding of cancer spread and advance individualized therapies and screening methods.

The study focuses on evaluating the genetic and phenotypic characteristics of CTCs/DTCs and cfDNA. It seeks to understand their role in cancer biology and potential for early detection.

  • Who can participate: Adults over 18 years with a diagnosis of solid cancer, including lung, esophageal, stomach, bile duct/pancreas, colorectal, melanoma, and sarcoma, can participate. High-risk individuals aged 55-80 years with a significant smoking history are also eligible.
  • Study details: Participants will provide blood, urine, and possibly bone marrow samples for analysis.
Study details
    Non Small Cell Lung Cancer
    Esophageal Cancer
    Gastric Cancer
    Pancreatic Cancer
    Hepatocellular Cancer
    Colorectal Cancer

NCT03551951

University of Missouri-Columbia

17 October 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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