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Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals

Investigating Early Detection Methods for Pancreatic Cancer in High-Risk Individuals

Recruiting
18 years and older
All
Phase 0

This study investigates pancreatic ductal adenocarcinoma. The purpose of this study is to see if adding blood-based tests and symptom review to standard screening can identify cancer early in high-risk individuals.

The study evaluates the combination of blood tests and symptom reviews with standard screening methods like endoscopic ultrasound and MRI to detect pancreatic cancer early. It assesses the effectiveness of these combined methods.

  • Who can participate: Adults aged 30 and older with certain genetic variants or family history of pancreatic cancer may participate. Participants must not have active pancreatic cancer or any active metastatic cancer and must be able to undergo screening procedures.
  • Study details: Participants will undergo blood tests and symptom reviews. A placebo is not involved in this study.
  • Study timelines: The study will last a minimum of 30 months and up to 20 years.
Study details
    Pancreatic Cancer
    Pancreatic Ductal Adenocarcinoma
    PDAC
    PDAC - Pancreatic Ductal Adenocarcinoma
    Pancreatic Neoplasm

NCT06122896

Dana-Farber Cancer Institute

31 July 2026

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