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Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes（CAR-T） for CEA Positive Advanced Malignant Solid Tumors

Study of Investigational CAR-T Therapy for Advanced CEA-Positive Malignant Tumors

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates the use of investigational CAR-T cell therapy for advanced CEA-positive malignant tumors.

The purpose of this study is to evaluate the safety and effectiveness of the investigational CAR-T cell therapy. Researchers will observe how the therapy affects patients with CEA-positive advanced malignancies.

  • Who can participate: Adults 18 years and older with advanced malignant tumors, such as colorectal, esophageal, gastric, or pancreatic cancer, can participate. Participants should have experienced treatment failure after second-line standard therapies and have CEA-positive tumors confirmed by specific tests.
  • Study details: Participants will receive CAR-T cell therapy through either intravenous infusion or intraperitoneal injection. Some may receive a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.
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Study details
    Gastric Cancer
    Colon Cancer
    Rectal Cancer
    Breast Cancer
    Lung Cancer
    Esophagus Cancer
    Cholangiocarcinoma
    Pancreas Cancer

NCT06126406

Chongqing Precision Biotech Co., Ltd

8 April 2026

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