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LDRT Combined With Pucotenlimab and Standard Therapy for Advanced Pancreatic Cancer: A Single-Arm Study

Investigating Low-Dose Radiotherapy with Investigational Medication for Advanced Pancreatic Cancer

Recruiting
18-75 years
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates advanced pancreatic cancer. It explores the effects of low-dose radiotherapy combined with Pucotenlimab and standard therapy.

The study evaluates the safety, effectiveness, and feasibility of this combination treatment. It also looks at how these treatments might work together to improve patient outcomes.

  • Who can participate: Adults aged 18 years or older with confirmed pancreatic malignancy may participate. Key factors include an ECOG score of 0 to 1 and no prior PD-1 or PD-L1 inhibitor treatment.
  • Study details: Participants will receive a combination of low-dose radiotherapy, investigational medication, and standard chemotherapy. A placebo is not used in this study.
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Study details
    Pancreatic Cancer
    PD-L1
    PD-1 Inhibitor
    LDRT
    Proterizumab

NCT07312422

Zhejiang Provincial People's Hospital

31 July 2026

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