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The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation

Study on Metastatic Pancreatic Cancer Treatment

Recruiting
18 years and older
All
Phase 2

This study investigates metastatic pancreatic ductal adenocarcinoma. It evaluates the potential benefits of combining radiation therapy with immune checkpoint inhibitors.

The study focuses on assessing the safety and effectiveness of this combination treatment. It evaluates how well these therapies work together in patients with this condition.

  • Who can participate: Adults 18 years and older with a confirmed diagnosis of pancreatic ductal adenocarcinoma may participate. Eligibility includes measurable disease and a life expectancy of at least 3 months.
  • Study details: Participants will receive a combination of radiation therapy and immune checkpoint inhibitors. Some may receive a placebo, an inactive substance resembling the investigational medicine.
Study details
    Metastatic Pancreatic Ductal Adenocarcinoma
    Metastatic Pancreatic Cancer

NCT06843551

Benjamin Spieler

29 August 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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