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IN10018 in Combination With RNK08954 for the Treatment of KRASG12D Mutation-Positive Locally Advanced or Metastatic Solid Tumors

Study for KRASG12D Mutation-Positive Solid Tumors

Recruiting
18 years and older
All
Phase 1/2

This study investigates KRASG12D mutation-positive locally advanced or metastatic solid tumors. The purpose of this study is to explore the effects of an investigational medication when combined with another treatment.

The study evaluates the safety and effectiveness of the investigational medication combination. It looks at how well the treatment works against tumors and checks for any side effects.

  • Who can participate: Adults aged 18 and older with locally advanced or metastatic solid tumors that are KRASG12D mutation-positive can participate. Participants must have at least one measurable lesion and meet specific health criteria.
  • Study details: Participants will receive an investigational medication in combination with another treatment. A placebo may be part of the study.
Study details
    Solid Tumor Cancer
    PDAC

NCT07441174

InxMed (Shanghai) Co., Ltd.

31 July 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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