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Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

Study of Tumor Infiltrating Lymphocytes for Metastatic Cancer Treatment

Recruiting
18-72 years
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates the use of tumor infiltrating lymphocytes (TIL) for treating metastatic cancer. Metastatic cancer can affect various parts of the body such as the digestive tract, urinary system, breast, and ovaries.

The study evaluates whether specifically selected TIL can reduce tumor size and assesses the safety of this treatment in patients with metastatic cancer.

  • Who can participate: Adults aged 18 to 72 with certain types of metastatic cancer, such as gastrointestinal, hepatobiliary, genitourinary, breast, ovarian, or endocrine tumors, may join. Participants must have cancer that is not responding to standard treatments.
  • Study details: Participants will undergo surgery to remove a tumor for TIL generation. They will receive TIL therapy along with chemotherapy. An inactive substance that looks like the investigational medicine/vaccine but does not contain any medicine.
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Study details
    Metastatic Colorectal Cancer
    Metastatic Pancreatic Cancer
    Metastatic Ovarian Cancer
    Metastatic Breast Carcinoma
    Metastatic Endocrine Tumors/ Neuroendocrine Tumors

NCT01174121

National Cancer Institute (NCI)

17 October 2026

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