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KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

Investigational Medication for Advanced Solid Tumors

Recruiting
18 years and older
All
Phase 1

This study investigates advanced solid tumors. It will explore the effects of an investigational medication, which is a farnesyltransferase inhibitor (FTI), when used alone or with other treatments.

The focus is to evaluate the safety and overall effects of the investigational medication on patients with advanced solid tumors. The study will look at how well the medication is tolerated and its potential impacts.

  • Who can participate: Adults aged 18 and older with specific types of advanced solid tumors can join. Participants need to have measurable disease and meet health criteria, such as certain genetic mutations, performance status, and organ function.
  • Study details: Participants will receive either the investigational medication alone or in combination with other treatments. In some cases, a placebo might be used.
Study details
    Solid Tumors With HRAS Alterations
    Non Small Cell Lung Cancer (NSCLC)
    Colorectal Cancer (CRC)
    Pancreatic Ductal Adenocarcinoma (PDAC)
    Clear Cell Renal Cell Carcinoma (ccRCC)
    Renal Cell Carcinoma (Kidney Cancer)
    Non Clear Cell Renal Cell Carcinoma (nccRCC)

NCT06026410

Kura Oncology, Inc.

17 October 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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