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IRE Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy

Investigational Treatment for Locally Advanced Pancreatic Cancer

Recruiting
18 years and older
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates the treatment of locally advanced pancreatic cancer. It focuses on using irreversible electroporation (IRE) combined with a dual-function antibody.

The study evaluates the safety and effectiveness of this treatment approach. It seeks to provide more options for patients whose previous treatments were not successful.

  • Who can participate: Adults aged 18 and older with locally advanced pancreatic cancer who have previously undergone but did not respond to standard AG therapy are eligible. Participants must have a certain ECOG performance status score and adequate organ function.
  • Study details: Participants will receive the investigational treatment. A placebo is used in the study, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.
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Study details
    Pancreatic Adenocarcinoma Locally Advanced

NCT07306273

Ruijin Hospital

31 July 2026

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