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Study of CEA Targeting CAR-T (PTC13) in the Treatment of CEA-Positive Advanced Malignant Solid Tumors

Study on Investigational CAR-T Cell Therapy for CEA-Positive Advanced Malignant Tumors

Recruiting
18 years and older
All
Phase 1

This study investigates the use of chimeric antigen receptor (CAR)-T cells in treating carcinoembryonic antigen (CEA)-positive advanced malignant solid tumors. The purpose of this study is to evaluate the safety and tolerability of the investigational medication in patients with this condition.

The study focuses on assessing how well the investigational medication works and how safe it is for patients. It evaluates the medication's effects and determines the best dosage for further research.

  • Who can participate: Adults aged 18 and older with advanced malignant tumors, including colorectal and lung cancer, may join. Participants must have failed at least second-line standard therapy and show CEA positivity.
  • Study details: Participants will receive an investigational medication through an infusion. The study will monitor the effects of the medication, and some participants may receive a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.
Study details
    Colorectal Cancer
    Stomach Cancer
    Pancreatic Cancer
    Metastatic Cancer

NCT06821048

Weijia Fang, MD

31 July 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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