This study investigates CEA-targeted CAR-T cell therapy in patients with CEA-positive advanced solid tumors. The purpose of this study is to explore the potential effects of this investigational treatment on these tumors.
The study evaluates the safety and effectiveness of CEA-targeted CAR-T cells in a clinical setting. Researchers are interested in understanding how this treatment works and its impact on patients with these specific tumor types.
- Who can participate: Adults aged 18 and older with advanced, metastatic, or recurrent malignant tumors, including colorectal, esophageal, gastric, pancreatic, lung cancer, and cholangiocarcinoma, may participate. Participants must have CEA-positive tumors and have failed at least second-line standard treatment.
- Study details: Participants will receive an investigational CAR-T cell therapy targeting CEA-positive tumors.