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Treatment of Advanced Malignant Solid Tumors With Claudin18.2CAR-T

Investigational Treatment for Advanced Gastric and Pancreatic Cancer

Recruiting
18-75 years
All
Phase N/A

This study investigates advanced gastric cancer and pancreatic cancer. It focuses on evaluating the investigational treatment Claudin18.2CAR-T, which targets specific proteins found in these cancers.

The purpose of this study is to evaluate the safety and effectiveness of Claudin18.2CAR-T cells. Researchers are interested in how well this treatment works in improving outcomes for patients with these advanced cancers.

  • Who can participate: Adults aged 18 to 75 with advanced gastric or pancreatic cancer may join. Participants must have received prior standard treatments and have measurable disease. Claudin 18.2 expression in tumor tissues is required.
  • Study details: Participants will receive the investigational treatment. Some may receive a placebo, an inactive substance that looks like the investigational medicine but does not contain any medicine.
Study details
    Advanced Pancreatic Carcinoma
    Advanced Gastric Carcinoma

NCT05620732

Shenzhen University General Hospital

8 April 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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