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Binimetinib in Patients With BRAF Fusion-positive Low-grade Glioma or Pancreatic Cancer (Perfume)

Investigational medication for BRAF fusion-positive low-grade glioma and pancreatic cancer

Recruiting
12 years and older
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates low-grade glioma and pancreatic cancer with BRAF fusion or rearrangement. The purpose of this study is to evaluate an investigational medication in patients with these conditions.

The study evaluates the safety and efficacy of the investigational medication in patients with specific genetic markers. It focuses on understanding how well patients tolerate the treatment and any effects it may have.

  • Who can participate: Adults and children aged 12 years and older with low-grade glioma or pancreatic cancer may participate. Key eligibility includes having a BRAF fusion or rearrangement and measurable disease.
  • Study details: Participants will take an investigational medication orally. Some may receive a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.
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Study details
    Low-grade Glioma
    Pancreatic Cancer

NCT06159478

National Cancer Center, Japan

8 April 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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