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HRS-4642 With Nimotuzumab and Chemotherapy for First-line Treatment of Advanced Pancreatic Cancer Patients

Investigational Treatment for Advanced Pancreatic Cancer

Recruiting
18-75 years
All
Phase 2

This study investigates advanced pancreatic cancer with a specific KRAS G12D mutation. The purpose of this study is to evaluate the effectiveness of a combination treatment using investigational medication, nimotuzumab, and chemotherapy for patients who have not received prior systemic therapy for their advanced condition.

The study focuses on assessing the safety and effectiveness of the treatment combination. It evaluates how well patients tolerate the treatment and how it affects their condition. This study investigates the treatment's impact on the disease.

  • Who can participate: Adults aged 18 to 75 with advanced pancreatic cancer and a KRAS G12D mutation may be eligible if they have not received systemic therapy in the advanced stage and meet specific health criteria.
  • Study details: Participants will receive treatment, and the study will involve monitoring the effects on their health and condition. A placebo is not used in this study.
Study details
    Metastatic Pancreatic Carcinoma

NCT06770452

Zhejiang University

31 July 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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