This study investigates unresectable pancreatic ductal adenocarcinoma. The purpose is to understand the complex interactions of genetic, stromal, and immunological factors in this condition.
The study evaluates how these factors may affect treatment response and chemotherapy resistance. It looks into genetic differences between primary and metastatic tumor sites and changes in molecular profiles under drug pressure.
- Who can participate: Adults aged 18 to 79 years with a histological diagnosis of pancreatic ductal adenocarcinoma can participate. They must be fit for chemotherapy and willing to follow up at designated centers.
- Study details: Participants will provide tissue samples via endoscopic ultrasound fine needle biopsy for analysis.