This study investigates advanced pheochromocytoma/paraganglioma, pancreatic neuroendocrine tumors, von Hippel-Lindau disease-associated tumors, advanced gastrointestinal stromal tumors, and solid tumors with specific genetic alterations.
The study evaluates the safety and effectiveness of an investigational medication by measuring response rates in participants with these conditions.
- Who can participate: Participants must be at least 12 years old, with some groups requiring a minimum age of 18. Eligible participants should have a diagnosis of specific advanced tumors or genetic conditions.
- Study details: Participants will receive an investigational medication. Some participants may receive a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.