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A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

Investigation of Safety and Tolerability of Investigational Medication in Advanced Solid Tumors with KRAS Mutations

Recruiting
18 years and older
All
Phase 1

This study investigates advanced solid tumors with KRAS mutations. The purpose of this study is to evaluate the safety and tolerability of an investigational medication in adults with these conditions.

The study focuses on assessing the safety, tolerability, and preliminary clinical activity of the investigational medication. It also looks at how the body absorbs and processes the medication.

  • Who can participate: Adults with advanced solid tumors with KRAS mutations who have not had prior treatment with a KRAS inhibitor may be eligible. Participants should have an ECOG performance status of 0 or 1 and adequate organ function.
  • Study details: Participants will take the investigational medication to evaluate its effects. The study will include a dose escalation and dose expansion phase to assess different doses.
Study details
    Cancer
    PDAC - Pancreatic Ductal Adenocarcinoma
    NSCLC (Non-small Cell Lung Cancer)
    CRC (Colorectal Cancer)
    Advanced Solid Tumors

NCT06835569

Alterome Therapeutics, Inc.

31 July 2026

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