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Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Investigation of an Investigational Medication in Solid Tumors with MTAP Deletion

Recruiting
18 years and older
All
Phase 1

This study investigates solid tumors with MTAP deletion. It looks at how the investigational medication works in people with these tumors.

The study evaluates the safety and effects of the investigational medication. It focuses on how the body processes the medication and its potential impact on the tumors.

  • Who can participate: Adults aged 18 and older with a solid tumor that has an MTAP gene deletion may participate. Participants need to have unresectable or metastatic disease and meet certain health criteria.
  • Study details: Participants will receive the investigational medication to check its effects on their tumors. Some might receive a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.
Study details
    Mesothelioma
    Non Small Cell Lung Cancer
    Malignant Peripheral Nerve Sheath Tumors
    Solid Tumor
    Pancreatic Adenocarcinoma
    Advanced Solid Tumor

NCT05245500

Bristol-Myers Squibb

12 September 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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