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AOH1996 for the Treatment of Refractory Solid Tumors

Investigational Medication for Treating Solid Tumors That Do Not Respond to Treatment

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates the treatment of refractory solid tumors.

The study evaluates the safety and dosage of an investigational medication to determine the best dose for future studies. It also looks at how the medication is absorbed and its preliminary effectiveness.

  • Who can participate: Adults aged 18 and older with solid tumors that have not responded to standard treatments or who refuse standard treatments are eligible. Participants must have a performance status of 2 or less.
  • Study details: Participants will take the investigational medication orally twice daily. The study will also test the medication in combination with a TKI for certain patients.
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Study details
    Refractory Malignant Solid Neoplasm
    Osteosarcoma
    Leiomyosarcomas
    Synovial Sarcomas
    Ovarian Cancer
    Non-Small Cell Lung Cancer
    Pancreatic Cancer

NCT05227326

City of Hope Medical Center

1 August 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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