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Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Patients With Peritoneal Metastasis From Pancreatic Adenocarcinoma

Investigating PIPAC with Investigational Medication for Peritoneal Metastasis from Pancreatic Adenocarcinoma

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates the use of Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) for patients with peritoneal metastasis from pancreatic adenocarcinoma. PIPAC is a method that delivers chemotherapy directly to the abdominal cavity, potentially improving the reach and effectiveness of the treatment in the affected area.

The study evaluates the safety and effectiveness of combining PIPAC with nab-paclitaxel and standard care. It looks into whether this combination can improve patient outcomes by enhancing drug delivery to tumor sites without causing significant additional side effects.

  • Who can participate: Adults aged 18 and older with confirmed pancreatic adenocarcinoma and peritoneal metastasis may participate. Participants must meet specific health criteria, including adequate blood counts and liver function, and should not have extra-peritoneal metastasis or severe health conditions.
  • Study details: Participants will receive PIPAC with an investigational medication and standard care therapy.
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Study details
    Adenocarcinoma Pancreas

NCT07253662

Northwell Health

31 July 2026

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