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cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

Study on Early Cancer Detection and Minimal Residual Disease Using Investigational DNA Assay

Recruiting
40 years and older
All
Phase N/A

This study investigates the use of a cfDNA assay for early cancer detection and minimal residual disease. The cancers included are brain, breast, bladder, cervical, colorectal, endometrial, esophageal, gastric, head and neck, hepatobiliary, leukemia, lung, lymphoma, multiple myeloma, ovarian, pancreatic, prostate, renal, sarcoma, and thyroid.

The study focuses on evaluating the ability of the genome-wide methylome enrichment platform to detect minimal residual disease and relapse in lung cancer. It also looks at the detection of multiple cancer types using this platform.

  • Who can participate: Participants aged 40 or older with newly diagnosed or recurrent specific cancer types, or without cancer in the last 5 years, may be eligible.
  • Study details: Participants will provide blood samples and clinical data. Those with cancer will have follow-ups and blood draws after treatment. Control participants will have regular follow-ups.
  • Study visits: Participants will attend regular visits over a period of up to 3 years.
Study details
    Brain Cancer
    Breast Cancer
    Bladder Cancer
    Cervical Cancer
    Colorectal Cancer
    Endometrial Cancer
    Esophageal Cancer
    Stomach Cancer
    Head and Neck Cancer
    Hepatobiliary Cancer
    Leukemia
    Lung Cancer
    Lymphoma
    Multiple Myeloma
    Ovarian Cancer
    Pancreatic Cancer
    Prostate Cancer
    Renal Cancer
    Sarcoma
    Thyroid Cancer

NCT05366881

Adela, Inc

31 July 2026

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