This study investigates screening and differentiating common cancers using peripheral blood cell-free DNA sequencing. The study focuses on participants with or without suspicious lesions to determine the effectiveness of this method.

The study evaluates the ability of the developed model to screen and classify common cancers, especially in the early stages. It looks into the safety and effectiveness of using peripheral blood cell-free DNA sequencing for this purpose.

• Who can participate: Participants aged 20 to 79 years can join. Those newly diagnosed with certain cancers or individuals without a cancer diagnosis during routine exams are eligible. Exclusion criteria include active systemic diseases and recent cancer treatments.
• Study details: Participants will provide a blood sample of 15 to 20 ml. They may also receive 1 to 2 follow-up calls by telephone.