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CT-95 in Advanced Cancers Associated With Mesothelin Expression

Study on Investigational Antibody for Certain Cancers with Mesothelin Expression

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates advanced cancers associated with mesothelin expression. The purpose of this study is to evaluate the investigational medication.

The study evaluates the safety and effectiveness of the investigational medication. It focuses on understanding how well the medication works and how safe it is for participants.

  • Who can participate: Participants must have cancers with mesothelin expression and evaluable disease per RECIST 1.1 or mRECIST. They should have an ECOG score of 0 or 1 and adequate organ function.
  • Study details: Participants will receive the investigational medication intravenously once a week.
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Study details
    Mesothelin-Expressing Tumors
    Epithelial Ovarian Cancer
    Malignant Pleural Mesothelioma
    Advanced
    Malignant Peritoneal Mesothelioma
    Advanced
    Pancreatic Adenocarcinoma Advanced or Metastatic
    Lung Adenocarcinoma Metastatic
    Cholangiocarcinoma Advanced
    Cholangiocarcinoma Non-resectable
    Mesothelin-expressing Advanced Cancers
    Mesothelin-positive Advanced Malignant Solid Tumors
    Colorectal Cancer

NCT06756035

Context Therapeutics Inc.

31 July 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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