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mFOLFIRINOX Plus Radiotherapy to Patients With CA19-9-normal Advanced Pancreatic Cancer Refractory to Chemotherapy

Study on Investigational Treatment and Radiotherapy for Advanced Pancreatic Cancer with Normal CA19-9 Levels

Recruiting
18-80 years
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates advanced pancreatic cancer with normal CA19-9 levels. The purpose is to evaluate the combination of mFOLFIRINOX and radiotherapy for patients whose cancer has not responded to chemotherapy.

Researchers are evaluating how safe and effective the treatment is for patients with this specific type of pancreatic cancer. The study looks at various outcomes such as survival rates and disease control.

  • Who can participate: Adults aged 18 to 80 with advanced pancreatic adenocarcinoma, who have not responded to prior chemotherapy but have not received radiotherapy, may be eligible. Participants must have normal CA19-9 levels and meet specific health criteria.
  • Study details: Participants will receive mFOLFIRINOX combined with radiotherapy. The study measures include progression-free survival and other health outcomes. A placebo is not used in this study.
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Study details
    Pancreatic Cancer
    Radiotherapy

NCT06249321

Fudan University

31 July 2026

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