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AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors

Study of AVA6103 for Advanced Solid Tumors

Recruiting
18 years and older
All
Phase 1

This study investigates AVA6103 in patients with locally advanced or metastatic solid tumors. AVA6103 is being studied to understand its effects on these types of tumors which are likely to be FAP positive.

The study evaluates the safety and tolerability of AVA6103. Researchers will look at how patients respond to the investigational medication to determine the best dose for further studies.

  • Who can participate: Adults 18 years and older with certain FAP positive tumors like cervical/vulvar cancer, SCLC, gastric/GEJ cancer, and PDAC may participate. Participants must have tried all standard treatments or be ineligible for them.
  • Study details: Participants will receive AVA6103 intravenously. Some may receive an inactive substance called a placebo, which looks like the investigational medicine but does not contain any medicine.
Study details
    Vulvar Adenocarcinoma
    PDAC - Pancreatic Ductal Adenocarcinoma
    Gastric Adenocarcinoma
    GEJ Adenocarcinoma
    Cervical Adenocarcinoma
    Cervical Adenosquamous Carcinoma
    Small Cell Carcinoma of Lung
    Colorectal Cancer
    Hormone Receptor Positive Breast Carcinoma

NCT07454642

Avacta Life Sciences Ltd

30 July 2026

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